Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 258564Generated: October 24, 2026

1-Acetyl-6-aminoindoline

NSC 87623 · 1-ACETYLINDOLIN-6-AMINE · 6-Amino-N-acetylindoline · 1-Acetyl-6-aminoindoline · 1-Acetyl-6-aminoindoline 95+% · 1-(6-Aminoindolin-1-yl)ethanone · 1-(6-amino-1-indolinyl)ethanone · 1-Acetyl-6-aminoindoline powder

https://huagongshe.com/en/chemical/258564

1-Acetyl-6-aminoindoline molecular structure

Identifiers & Physical Properties

CAS No.62368-29-0
Molecular formulaC10H12N2O
Average molar mass176.21 g/mol
Monoisotopic mass176.094963 g/mol
SMILESCC(=O)N1CCc2ccc(N)cc21
InChIKeyLOZKZWIQDVEDCQ-UHFFFAOYSA-N
PubChem CID258564
ChEMBLCHEMBL1877102
EC No.622-695-5
DTXSIDDTXSID00293172

Chemical & Physical Properties

XLogP0.6
Topological polar surface area46.3
Hydrogen bond donors1
Hydrogen bond acceptors2
Rotatable bonds0
Heavy atoms13
Formal charge0
Complexity217
Melting point182 °C
Storage conditions2-8°C
Physical statepowder
Coloryellow to tan
InChI1S/C10H12N2O/c1-7(13)12-5-4-8-2-3-9(11)6-10(8)12/h2-3,6H,4-5,11H2,1H3
InChIKeyLOZKZWIQDVEDCQ-UHFFFAOYSA-N
SMILESCC(=O)N1CCc2ccc(N)cc12
UNSPSC Code12352100
NACRESNA.22
GHS pictogramGHS07
Signal wordWarning
GHS hazard statementsH302
GHS precautionary statementsP264-P270-P301+P312-P501
Personal protective equipment (PPE)dust mask type N95 (US), Eyeshields, Gloves
Hazard symbolsXn,Xi
Risk statements (R)22
Water hazard class (WGK)3
Hazard NoteIrritant
Customs code2933998090
Storage class11 - Combustible Solids
Hazard classAcute Tox. 4 Oral

Safety & Regulations

GHS classificationWarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 42 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Personal protective equipment (PPE)dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK)3
Customs code2933998090
Risk statements (R)22
Signal wordWarning
GHS pictogramGHS07
Hazard symbolsXn,Xi
hazard_noteIrritant
Storage class11 - Combustible Solids
GHS hazard statementsH302
Hazard classAcute Tox. 4 Oral
GHS precautionary statementsP264-P270-P301+P312-P501

Applications & Uses

Uses

Reactant for preparation of:Transient receptor potential cation channel V1 (TRPV1) antagonistsInhibitor of the human immunodeficiency virus (HIV) envelope glycoprotein gp120 binding to the cluster of differentiation 4 (CD4) receptorAntiproliferative agentsSerotonin 5-HT2C/2B receptor antagonists

Uses

1-Acetyl-6-aminoindoline is a reactant in the synthesis of anilines, phenols, and heterocycles with aryl iodides.