2-Fluoro-4-methylpyridin-3-amine

HCID 2763161CAS 173435-32-0

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Basic information

Standard SMILES: Cc1ccnc(F)c1N
InChIKey: ZKQQKPXTKXTEQR-UHFFFAOYSA-N
Molecular formula: C6H7FN2
Average molar mass: 126.13 g/mol
Monoisotopic mass: 126.05932644

Names & identifiers

Preferred name: 2-Fluoro-4-methylpyridin-3-amine
IUPAC: 2-fluoro-4-methylpyridin-3-amine
English name: 3-Amino-2-fluoro-4-picoline
Molecular formula: C6H7FN2
Molecular weight: 126.13

Names & synonyms

2-fluoro-4-methylpyridin-3-amine173435-32-0DTXSID20376774RefChem:1063102DTXCID203278023-Amino-2-fluoro-4-picoline3-AMINO-2-FLUORO-4-METHYLPYRIDINEMFCD041125563-PYRIDINAMINE, 2-FLUORO-4-METHYL-2-fluoro-4-methyl-pyridin-3-amineSCHEMBL7849737SCHEMBL30905975

Show more names

3-Amino-2-fluoro-4-methylpyridin2-Fluoro-4-methyl-3-pyridinamine3-Pyridinamine,2-fluoro-4-methyl-2-Fluoro-4-methyl-pyridin-3-ylamine3-Amino-2-fluoro-4-methylpyridine,98%3-Pyridinamine,2-fluoro-4-methyl-(9CI)3-AMINO-2-FLUORO-4-PICOLINE ISO 9001：2015 REACH

ZKQQKPXTKXTEQR-UHFFFAOYSA-N2-fluoro-4-methyl-3-pyridylamineSBB069831AKOS006342461AB17625CS-W021693DS-11263SY101418

Database identifiers

CAS: 173435-32-0
PubChem CID: 2763161
DTXSID: DTXSID20376774

Properties

Computed structural properties

XLogP: 1
Topological polar surface area: 38.9 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 3
Rotatable bonds: 0
Heavy atoms: 9
Formal charge: 0
Complexity: 97.1

Physicochemical properties

Melting point: 63 · 63-64℃
Boiling point: 260.8 · 260.8±35.0 °C(Predicted)
Density: 1.196 · 1.196±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 1.16 · 1.16±0.18(Predicted)
form: Solid
color: Off-white
CAS DataBase Reference: 173435 · 173435-32-0(CAS DataBase Reference)
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 302 · H302-H312-H315-H319-H332-H335
Precautionary statements: 261 · P261-P280-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes: T
HS Code: 2933399990 · 2933399990

Safety & regulation

Safety data

hs_code: 2933399990
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: T
Hazard statements: H302-H312-H315-H319-H332-H335
Precautionary statements: P261-P280-P304+P340-P305+P351+P338-P405-P501a

Chemistry & industry

Applications · 1 item

Uses2-Fluoro-4-methylpyridin-3-amine is auseful reactant in the synthesis of phenylsulfonamidomethylbenzamides, oxopyridopyrrolopyrazinyacetamides, carbamoylalkylthiophenylmethylpicolinamides and benzylthiotriazolylpyridines, which exhibit SAR and kappa opioid receptor agonistic and antagonistic activity.