HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Morpholin-4-yl)pyridine-3-carbaldehyde
6-MORPHOLINONICOTINALDEHYDE · 6-morpholin-4-ylnicotinaldehyde · 6-Morpholinylpyridine-3-carboxaldehyde · 6-MORPHOLIN-4-YL-PYRIDINE-3-CARBALDEHYDE · 6-(4-Morpholinyl)-3-pyridinecarboxaldehyde · 6-MORPHOLIN-4-YL-PYRIDINE-3-CARBOXALDEHYDE · 3-Pyridinecarboxaldehyde, 6-(4-morpholinyl)- · 6-(Morpholin-4-yl)pyridine-3-carboxaldehyde, 4-(5-Formylpyridin-2-yl)morpholine
Identifiers & Physical Properties
| CAS No. | 173282-60-5 |
|---|---|
| Molecular formula | C10H12N2O2 |
| Average molar mass | 192.21 g/mol |
| Monoisotopic mass | 192.08987762 g/mol |
| SMILES | O=Cc1ccc(N2CCOCC2)nc1 |
| InChIKey | VZEANTSDLFVWCK-UHFFFAOYSA-N |
| PubChem CID | 2776463 |
| EC No. | 878-142-5 |
| DTXSID | DTXSID30380100 |
Chemical & Physical Properties
| XLogP | 0.4 |
|---|---|
| Topological polar surface area | 42.4 |
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 4 |
| Rotatable bonds | 2 |
| Heavy atoms | 14 |
| Formal charge | 0 |
| Complexity | 193 |
| Melting point | 86-88°C |
| Boiling point | 395.8±42.0 °C(Predicted) |
| Density | 1.219±0.06 g/cm3(Predicted) |
| Storage conditions | Sealed in dry,2-8°C |
| pKa (acidity coefficient) | 3.58±0.10(Predicted) |
| Physical state | solid |
| Color | Yellow |
| InChI | 1S/C10H12N2O2/c13-8-9-1-2-10(11-7-9)12-3-5-14-6-4-12/h1-2,7-8H,3-6H2 |
| InChIKey | VZEANTSDLFVWCK-UHFFFAOYSA-N |
| SMILES | O=Cc1ccc(nc1)N2CCOCC2 |
| CAS DataBase Reference | 173282-60-5 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H302+H312+H332 |
| GHS precautionary statements | P280-P301+P312-P362+P364 |
| Hazard symbols | Xi,Xn |
| Risk statements (R) | 36/37/38-22 |
| Safety statements (S) | 26-36/37/39 |
| Water hazard class (WGK) | WGK 3 |
| Hazard class | IRRITANTAcute Tox. 4 Oral |
| Customs code | 2933399990 |
| Storage class | 11 - Combustible Solids |
Safety & Regulations
| GHS classification | WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| Water hazard class (WGK) | WGK 3 |
| Customs code | 2933399990 |
| Risk statements (R) | 36/37/38-22 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | Xi,Xn |
| Safety statements (S) | 26-36/37/39 |
| Hazard class | IRRITANTAcute Tox. 4 Oral |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H302+H312+H332 |
| GHS precautionary statements | P280-P301+P312-P362+P364 |
Applications & Uses
Uses
6-MorpholinonicotinaldehydeUsed in the preparation of substituted benzamide derivatives and analogs for use as hematopoietic growth factor receptor activators.