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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 3815654Generated: October 23, 2026

2-(2-Methoxyethoxy)ethyl methanesulfonate

mPEG2-OMs · m-PEG2-Ms · Methyl-PEG2-MS · 2-(2-Methoxyethoxy)ethyl methanesulfonate · methanesulfonicacid2-(2-methoxyethoxy)ethylester · Ethanol, 2-(2-methoxyethoxy)-, 1-methanesulfonate

https://huagongshe.com/en/chemical/3815654

2-(2-Methoxyethoxy)ethyl methanesulfonate molecular structure

Identifiers & Physical Properties

CAS No.60696-83-5
Molecular formulaC6H14O5S
Average molar mass198.24 g/mol
SMILESCOCCOCCOS(C)(=O)=O
InChIKeyFCHYIMQJCGYDPR-UHFFFAOYSA-N
PubChem CID3815654
EC No.893-296-3

Chemical & Physical Properties

XLogP-0.6
Topological polar surface area70.2
Hydrogen bond donors0
Hydrogen bond acceptors5
Rotatable bonds7
Heavy atoms12
Formal charge0
Complexity181

Safety & Regulations

GHS classificationWarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard Classes and CategoriesAcute Tox. 4 (100%)

Applications & Uses

Description

m-PEG3-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].