Cefpirome

HCID 5479539CAS 84957-29-9

Completing data — usually done within a minute

Substructure searchFind similar structures

Basic information

Standard SMILES
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3cccc4c3CCC4)CS[C@H]12)c1csc(N)n1
InChIKey
DKOQGJHPHLTOJR-WHRDSVKCSA-N
Molecular formula
C22H22N6O5S2
Average molar mass
514.589 g/mol
Monoisotopic mass
514.1093098

Names & identifiers

Preferred name
Cefpirome
IUPAC
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(6,7-dihydro-5H-cyclopenta[b]pyridin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
English name
Cefpirome
Molecular formula
C22H22N6O5S2
Molecular weight
514.58

Names & synonyms

CEFPIROME SULPHATEHR-810KeitimCS-283CEFPIROMECefpiromaCefpiromumCerfpiromeCefpirome-13C-D3Cefpiromum [latin]

Database identifiers

CAS
84957-29-9
PubChem CID
5479539
DTXSID
DTXSID2048244
ChEMBL
CHEMBL65794
ChEBI
CHEBI:3503
UNII
S72Q2F09HY
Nikkaji
J32.848K

Properties

Physicochemical properties

storage temp.
2 · 2-8°C(protect from light)
FDA UNII
72 Q2F09HY · S72Q2F09HY
ATC code
1 DE02 · J01DE02
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
302 · H302-H315-H319-H335

Safety & regulation

Safety data

Toxicity
LD50 in mice, rats (g/kg): 1.9-2.4, 1.9-2.15 i.v.; 3.8-4.2, 5.8-6.55 i.p. (Donaubauer, Mayer)
risk_code
36/37/38-42/43
Signal word
Warning
Symbol(GHS)
GHS07
hazard_code
Xi
safety_code
22-26-36/37/39

Chemistry & industry

Applications · 2 items

DescriptionThis drug is resistant with respect to a broad spectrum of beta-lactamases. Its spectrum of activity is analogous to that of the third-generation cephalosporin cefotaxime (32.1.2.56), although it is more active with respect to some staphylococci, enterococci, and also a few enterobacteria. Synonyms of this drug are cefrom, cedixen, and others.

UsesCephalosporin antibiotic Claforan

Upstream & downstream products

Suppliers50 total

北京华美互利生物化工010-56205725 · [email protected]
上海莉凯化工技术有限公司16628776521 · [email protected]
深圳市健竹科技有限公司0755-89218110 13480856786
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
Additional notes · 1 item

DefinitionChEBI: Cefpirome is a fourth-generation cephalosporin antibiotic having 6,7-dihydro-5H-cyclopenta[b]pyridinium-1-ylmethyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively. It is a cyclopentapyridine and a cephalosporin.

Related reactions

0 records
New reaction record

No reaction records under the current filter.

Linked notes

Loading…