Ethyl {4-[6-({5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}amino)-2-methylpyrimidin-4-yl]piperazin-1-yl}acetate

HCID 57940725CAS 910297-62-0

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Basic information

Standard SMILES: CCOC(=O)CN1CCN(c2cc(Nc3ncc(C(=O)Nc4c(C)cccc4Cl)s3)nc(C)n2)CC1
InChIKey: LTKNTZZGCSNLFZ-UHFFFAOYSA-N
Molecular formula: C24H28ClN7O3S
Average molar mass: 530.054 g/mol
Monoisotopic mass: 529.16628644

Names & identifiers

Preferred name: Ethyl {4-[6-({5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}amino)-2-methylpyrimidin-4-yl]piperazin-1-yl}acetate
IUPAC: Ethyl {4-[6-({5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}amino)-2-methylpyrimidin-4-yl]piperazin-1-yl}acetate
English name: 4-[6-[[5-[[(2-Chloro-6-Methylphenyl)aMino]carbonyl]-2-thiazolyl]aMino]-2-Methyl-4-pyriMidinyl]-1-piperazineacetic Acid Ethyl Ester
Molecular formula: C24H28ClN7O3S
Molecular weight: 530.04

Names & synonyms

Dasatinib Carboxylic Acid Ethyl Esterethyl 2-[4-[6-[[5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl]amino]-2-methylpyrimidin-4-yl]piperazin-1-yl]acetate4-[6-[[5-[[(2-Chloro-6-Methylphenyl)aMino]carbonyl]-2-thiazolyl]aMino]-2-Methyl-4-pyriMidinyl]-1-piperazineacetic Acid Ethyl Ester1-Piperazineacetic acid, 4-[6-[[5-[[(2-chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-, ethyl ester

Database identifiers

CAS: 910297-62-0
PubChem CID: 57940725
DTXSID: DTXSID60728430

Properties

Physicochemical properties

Melting point: 273 · 273-275°C
Density: 1.375 · 1.375±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
pka: 10.94 · 10.94±0.70(Predicted)
form: Solid
color: White to Off-White

Chemistry & industry

Applications

UsesProtected Dasatinib Carboxylic Acid (D193605). An oxidative metabolite of Dasatinib (M6 metabolite); used in the treatment of cancers and immune diseases. It is a COVID19-related research product.

UsesProtected Dasatinib Carboxylic Acid (D193605). Dasatinib Carboxylic Acid Ethyl Ester is an oxidative metabolite of Dasatinib (M6 metabolite); used in the treatment of cancers and immune diseases.