HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-(Diphenylphosphino)ethyl)pyridine
diphenyl(2-pyridin-2-ylethyl)phosphane · 2-[2-(DIPHENYLPHOSPHINO)ETHYL]PYRIDINE · 2-[2-(diphenylphosphanyl)ethyl]pyridine · Diphenyl(2-(pyridin-2-yl)ethyl)phosphine · Pyridine,2-[2-(diphenylphosphino)ethyl]- · 1-(Diphenylphosphino)-2-(2-pyridyl)ethane · 2-[2-(Diphenylphosphino)ethyl]pyridine,97% · 2-[2-(Diphenylphosphino)ethyl]pyridine,min.97%
Identifiers & Physical Properties
| CAS No. | 10150-27-3 |
|---|---|
| Molecular formula | C19H18NP |
| Average molar mass | 291.3 g/mol |
| Monoisotopic mass | 291.11768621 g/mol |
| SMILES | c1ccc(P(CCc2ccccn2)c2ccccc2)cc1 |
| InChIKey | ARSGXAZDYSTSKI-UHFFFAOYSA-N |
| PubChem CID | 611860 |
| EC No. | 634-431-6 |
| DTXSID | DTXSID90346404 |
Chemical & Physical Properties
| XLogP | 3.6 |
|---|---|
| Topological polar surface area | 12.9 |
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 1 |
| Rotatable bonds | 5 |
| Heavy atoms | 21 |
| Formal charge | 0 |
| Complexity | 263 |
| Melting point | 58-62 °C |
| Boiling point | 422.2±28.0 °C(Predicted) |
| Storage conditions | under inert gas (nitrogen or Argon) at 2-8°C |
| pKa (acidity coefficient) | 5.56±0.12(Predicted) |
| Physical state | Powder |
| Color | white |
| Sensitivity | air sensitive |
| InChI | 1S/C19H18NP/c1-3-10-18(11-4-1)21(19-12-5-2-6-13-19)16-14-17-9-7-8-15-20-17/h1-13,15H,14,16H2 |
| InChIKey | ARSGXAZDYSTSKI-UHFFFAOYSA-N |
| SMILES | C(Cc1ccccn1)P(c2ccccc2)c3ccccc3 |
| CAS DataBase Reference | 10150-27-3 |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Target organs | Respiratory system |
| Personal protective equipment (PPE) | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard symbols | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
| Water hazard class (WGK) | 3 |
| Storage class | 11 - Combustible Solids |
| Hazard class | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Safety & Regulations
| GHS classification | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 67 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Personal protective equipment (PPE) | dust mask type N95 (US), Eyeshields, Gloves |
| Water hazard class (WGK) | 3 |
| Risk statements (R) | 36/37/38 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | Xi |
| Safety statements (S) | 26 |
| Storage class | 11 - Combustible Solids |
| Target organs | Respiratory system |
| GHS hazard statements | H315-H319-H335 |
| Hazard class | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| GHS precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Applications & Uses
Uses
2-(2-(Diphenylphosphino)ethyl)pyridine is an important chiral catalyst with excellent catalytic activity. 2-(2-(Diphenylphosphino)ethyl)pyridine is widely used in asymmetric synthesis reactions, especially in the field of compound synthesis. 2-(2-(Diphenylphosphino)ethyl)pyridine can also be used in metal-catalyzed reactions to improve the selectivity and yield of the reaction.