Leucomycin, (2R,3R)-2,3-dihydroxybutanedioate (1:?)

HCID 6450271CAS 37280-56-1
Substructure searchFind similar structures

Basic information

Standard SMILES
CO[C@@H]1[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@@H]3CC(C)(C)[C@H](O)[C@@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@@H](C)OC(=O)C[C@H]1O.O=C(O)C(O)C(O)C(=O)O
InChIKey
LCDBILLRZFJKMN-RKYMYSRXSA-N
Molecular formula
C40H67NO18
Average molar mass
850 g/mol

Names & identifiers

Preferred name
Leucomycin, (2R,3R)-2,3-dihydroxybutanedioate (1:?)
IUPAC
2,3-dihydroxybutanedioic acid;2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-4-(dimethylamino)-3-hydroxy-5-[(2R,5S,6R)-5-hydroxy-4,4,6-trimethyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
English name
Kitasamycin tartrate
Molecular formula
C40H67NO18
Molecular weight
936.06

Names & synonyms

kitasamycin tartrateIPN75MD9DRLeucomycin, (R-(R*,R*))-2,3-dihydroxybutanedioate (salt)Leucomycin, (2R,3R)-2,3-dihydroxybutanedioate (1:?)TRUBINRefChem:1088434253-442-337280-56-1EINECS 253-442-3UNII-IPN75MD9DRKitasamycin tartrate [JAN]2,3-dihydroxybutanedioic acid;2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-4-(dimethylamino)-3-hydroxy-5-[(2R,5S,6R)-5-hydroxy-4,4,6-trimethyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
Show more names
C13500leucomycintartrateADM North tartrateTartarickitasamycinKITASAMYCINTRTARATEGuitamycin tartratenorfloxacin noctinickitasamycine tartrateKitasamycin tartrate USP/EP/BP
orb17054242-((4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-4-(dimethylamino)-3-hydroxy-5-(((2R,5S,6R)-5-hydroxy-4,4,6-trimethyltetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl)acetaldehyde 2,3-dihydroxysuccinateNS00127383

Database identifiers

CAS
37280-56-1
PubChem CID
6450271
EC Number
253-442-3

Properties

Computed structural properties

Topological polar surface area
289 Ų
Hydrogen bond donors
8
Hydrogen bond acceptors
19
Rotatable bonds
11
Heavy atoms
59

Physicochemical properties

Melting point
125 °C · 125 °C
storage temp.
-20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated)
form
Solid
color
Pale Yellow
Stability
Hygroscopic

Safety & regulation

Hazard information

Other Safety InformationIMAP assessments - Leucomycin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (salt): Environment tier I assessment

Chemistry & industry

Applications

UsesAntibacterial.

UsesLeucomycin tartrate (CAS# 37280-56-1) is an antibiotic and has been used in the treatment of nongonococcal urethritis with higher cure rates than the typically prescribed antibiotic, erythromycin (E649950).

Upstream & downstream products

Upstream raw materials

Suppliers50 total

湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
Hebei Zhuanglai Chemical Trading Co Ltd+86-16264648883 · [email protected]
HubeiwidelychemicaltechnologyCo.,Ltd18627774460 · [email protected]
清宁生物（江苏博泉生物科技有限公司）19352250998 · [email protected]
湖北海克斯生化有限公司17362916295; 17362916295 · [email protected]

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