| GHS classification | This chemical does not meet GHS hazard criteria for 95.6% (328 of 343) of all reports.Not ClassifiedAggregated GHS information provided per 343 reports by companies from 9 notifications to the ECHA C&L Inventory. |
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| Regulatory information | Chemical: 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt (1:1)Regulation (EC) No 1831/2003 (amended)1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.Status: Active Update: 29-03-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14605Sodium saccharin: Does not have an individual approval but may be used under an appropriate group standard |
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| Other safety information | Evaluation - Chemicals that are unlikely to require further regulation to manage risks to environment |
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| Fire hazards | Flash point data are not available for this chemical, but it is probably combustible. (NTP, 1992) |
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| Health hazards | SYMPTOMS: Symptoms of ingestion of this compound include nausea, vomiting and diarrhea. It may also cause anorexia. Inhalation may result in coughing and sneezing. |
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| Hazards summary | Causes changes in psychophysiological tests in acute oral studies of monkeysCauses kidney and bladder changes in 36-week constant oral studies of rats[RTECS] Usually contains about 5% water[NTP] Acceptable daily intake (ADI) of 0-5 mg/kg[JECFA] The dihydrate is CAS# 6155-57-3Contains 5-6% waterMay cause mechanical eye irritation[Mallinckrodt Baker MSDS] |
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| Reactive group | Amines, Phosphines, and Pyridines |
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| Reactivity Profile | This compound may react with oxidizing agents. (NTP, 1992). Very weak base in aqueous solution. |
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| Air and Water Reactions | Water soluble. |
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| Hazard Classes and Categories | Not Classified |
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| Fire fighting | Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992) |
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| First aid | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
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| Nonfire spill response | SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
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| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992) |
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