HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionamide
PROPANAMIDE · Propionamid · Amid kyseliny propionove · bdpg · Propiomide · propylamide · Propinamide · PROPIONAMIDE
Identifiers & Physical Properties
| CAS No. | 79-05-0 |
|---|---|
| Molecular formula | C3H7NO |
| Average molar mass | 73.09 g/mol |
| Monoisotopic mass | 73.05276385 g/mol |
| SMILES | CCC(N)=O |
| InChIKey | QLNJFJADRCOGBJ-UHFFFAOYSA-N |
| PubChem CID | 6578 |
| ChEMBL | CHEMBL1235716 |
| ChEBI | CHEBI:45422 |
| EC No. | 201-172-1 |
| DTXSID | DTXSID3058820 |
Chemical & Physical Properties
| XLogP | -0.7 |
|---|---|
| Topological polar surface area | 43.1 |
| Hydrogen bond donors | 1 |
| Hydrogen bond acceptors | 1 |
| Rotatable bonds | 1 |
| Heavy atoms | 5 |
| Formal charge | 0 |
| Complexity | 42 |
| Vapor pressure | 0.03 [mmHg]1.06Pa at 25℃ |
| Physical Description | Solid[Merck Index] Off-white crystalline flakes[Alfa Aesar MSDS] |
| Kovats Retention Index | 98418221792180118211807 |
| Melting point | 76-79 °C (lit.) |
| Boiling point | 213 °C (lit.) |
| Density | 1.042 g/mL at 25 °C (lit.) |
| Refractive index | nD110 1.4160 |
| Flash point | 213°C |
| Storage conditions | Store below +30°C. |
| Solubility | SOLUBLE |
| Physical state | Crystalline Powder |
| pKa (acidity coefficient) | 16.60±0.40(Predicted) |
| Specific gravity | 1.042 |
| Color | White to slightly yellow |
| Merck | 14,7824 |
| Henry's law constant | 3.3×103 mol/(m3Pa) at 25℃, Plyasunov et al. (2001) |
| InChI | 1S/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5) |
| InChIKey | QLNJFJADRCOGBJ-UHFFFAOYSA-N |
| SMILES | CCC(N)=O |
| LogP (partition coefficient) | -0.7 at 23℃ |
| CAS DataBase Reference | 79-05-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | QK07G0HP47 |
| NIST Chemistry Reference | Propanamide(79-05-0) |
| EPA Substance Registry System | Propanamide (79-05-0) |
| UNSPSC Code | 12352111 |
| NACRES | NA.22 |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H319 |
| GHS precautionary statements | P264-P280-P305+P351+P338-P337+P313 |
| Hazard symbols | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 24/25-36/37/39-26-37/39 |
| Water hazard class (WGK) | 3 |
| RTECS number | UE2975000 |
| TSCA inventory status | TSCA listed |
| Customs code | 29241900 |
| Storage class | 11 - Combustible Solids |
| Hazard class | Eye Irrit. 2 |
| REACH registrations | Active |
Safety & Regulations
| GHS classification | WarningH302 (83.3%): Harmful if swallowed [Warning Acute toxicity, oral]H319 (16.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 48 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatory information | Chemical: PropanamideStatus: Active Update: 09-09-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/30038Propanamide: Does not have an individual approval but may be used under an appropriate group standard |
| Hazards summary | May cause irritation[Alfa Aesar MSDS] See Dimethyl acetamide. |
| Hazard Classes and Categories | Acute Tox. 4 (83.3%)Eye Irrit. 2 (16.7%) |
| Adverse effects | Neurotoxin - Acute solvent syndrome |
| Toxicity Data | LCLo (rat) = 8,000 ppm |
| Water hazard class (WGK) | 3 |
| TSCA inventory status | TSCA listed |
| RTECS number | UE2975000 |
| Customs code | 29241900 |
| Risk statements (R) | 22-36/37/38 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | Xn |
| Safety statements (S) | 24/25-36/37/39-26-37/39 |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H319 |
| REACH registrations | Active |
| Hazard class | Eye Irrit. 2 |
| GHS precautionary statements | P264-P280-P305+P351+P338-P337+P313 |
Applications & Uses
Uses
Propionamide was used as adsorbent in the determination of adsorption isotherms of acetamide and propionamide on multi-wall carbon nanotube. It was used in a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.
General Description
Propionamide on γ-irradiation reacts with sulfur dioxide and this reaction has been studied by ESR spectroscopy, gas absorption measurements and X-ray diffraction.