(1S,2S)-1,2-diphenylethane-1,2-diamine

HCID 6931238CAS 16635-95-3
Substructure searchFind similar structures

Basic information

Standard SMILES
N[C@@H](c1ccccc1)[C@@H](N)c1ccccc1
InChIKey
PONXTPCRRASWKW-KBPBESRZSA-N
Molecular formula
C14H16N2
Average molar mass
212.29 g/mol
Monoisotopic mass
212.13134852

Names & identifiers

Preferred name
(1S,2S)-1,2-diphenylethane-1,2-diamine
IUPAC
(1S,2S)-1,2-diphenylethane-1,2-diamine
English name
1,2-Diphenylethylenediamine
Molecular formula
C14H16N2
Molecular weight
212.29

Names & synonyms

(1S,2S)-1,2-diphenylethane-1,2-diamineRefChem:393988608-420-129841-69-8(1S,2S)-(-)-1,2-Diphenylethylenediamine(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamineMFCD00082751(1s,2s)-1,2-diphenyl-1,2-ethanediamine1,2-Ethanediamine, 1,2-diphenyl-, (1S,2S)-(-)-1,2-diphenylethylenediamine(1s,2s)-1,2-diphenylethylenediamine16635-95-3
Show more names
TRANS-STILBENE1,2-DIPHENYLETHYLENESTILBENE, TRANS-DL-1,2-Diphenyl-1,2-ethanediamineBibenzilBIBENZALTRANS-TOLUYLENETRANS-BIBENZYLIDENESTILBENE, trans-(RG)TRANS-1,2-DIPHENYLETHYLENE
(S,S)-DPEN(+/-)-Stilbenediamine(1S,2S)-(-)-1,2-Diamino-1,2-diphenylethane(-)-STILBENEDIAMINErac-1,2-Diphenylethane-1,2-diaminedl-StilbenediamineNSC-167211((1S,2S)-2-Amino-1,2-diphenylethyl)amine; (-)-Stilbenediamine; (S,S)-1,2-Diamino-1,2-diphenylethane; (S,S)-1,2-Diphenylethylene-1,2-diamine;

Database identifiers

CAS
16635-95-3、29841-69-8
PubChem CID
6931238
DTXSID
DTXSID20426127
ChEMBL
CHEMBL467308
UNII
9BB7UW58PU、W52J5QHV92
EC Number
605-438-1、608-420-1
Nikkaji
J276.439C

Properties

Computed structural properties

XLogP
1.4
Topological polar surface area
52 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
2
Rotatable bonds
3
Heavy atoms
16

Physicochemical properties

Melting point
123 · 123-125 °C(lit.)
Boiling point
305 · 305-307 °C744 mm Hg(lit.)
Density
0.97 g/mL · 0.97 g/mL at 25 °C(lit.)
storage temp.
2 · Keep in dark place,Inert atmosphere,2-8°C
solubility
soluble in Methanol
form
powder to crystal

Safety & regulation

GHS classification

GHS Classification · 6 items

Warning

H315 (91.8%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (89.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (89.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Hazard Classes and Categories · 2 items

Acute Tox. 4 (50%)；Skin Irrit. 2 (100%)；Eye Irrit. 2 (100%)

Skin Irrit. 2 (91.8%)；Eye Irrit. 2 (89.8%)；STOT SE 3 (89.8%)

Safety data

wgk
2
rtecs
WJ4926500
ridadr
2735
hs_code
2921.59.8090
risk_code
22-36-51/53
Signal word
Warning

Chemistry & industry

Applications · 1 item

Uses1,2-Diphenylethylenediamine (DPE) has been found to react in a neutral medium with catecholamines and other catechol compounds in the presence of hexacyanoferrate(III) to give a compound that fluoresces intensely. The reaction is accelerated by amino acids such as glycine. Nohta et al. described a sensitive spectrofluorimetric method for determining catecholamines with 1,2diphenylethylenediamine. The method is based on the reaction of catechol compounds in a neutral medium with 1,2-diphenylethylenediamine in the presence of hexacyanoferrate(II1) and glycine at ambient temperature. The fluorescence shows excitation and emission maxima around 345 and 480 nm, respectively. The method is simple, selective for catechol compounds, and very sensitive. Catecholamines can be determined at concentrations as low as 15-20 pmol ml-1[1].

Upstream & downstream products

Suppliers50 total

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
绍兴赜军生物医药科技有限公司0575-82126188 15395856318
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
成都丽凯手性技术有限公司028-85247892 · [email protected]

Related reactions

5 records
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Linked notes

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