HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridineethanamine
2-(2-PYRIDYL)ETHYLAMINE · 2-(2-AMINOETHYL)PYRIDINE · 2-(PYRIDIN-2-YL)ETHANAMINE · lilly04432 · Demethylbetahistine · 2-PYRIDYLETHYLAMINE · RARECHEM AL BW 0258 · 2-aminoethylpyridine
Identifiers & Physical Properties
| CAS No. | 2706-56-1 |
|---|---|
| Molecular formula | C7H10N2 |
| Average molar mass | 122.17 g/mol |
| Monoisotopic mass | 122.08439833 g/mol |
| SMILES | NCCc1ccccn1 |
| InChIKey | XPQIPUZPSLAZDV-UHFFFAOYSA-N |
| PubChem CID | 75919 |
| ChEMBL | CHEMBL32813 |
| ChEBI | CHEBI:74024 |
| EC No. | 220-295-1 |
| DTXSID | DTXSID5022196 |
Chemical & Physical Properties
| XLogP | 0.1 |
|---|---|
| Topological polar surface area | 38.9 |
| Hydrogen bond donors | 1 |
| Hydrogen bond acceptors | 2 |
| Rotatable bonds | 2 |
| Heavy atoms | 9 |
| Formal charge | 0 |
| Complexity | 73 |
| Kovats Retention Index | 11471768 |
| Melting point | 198-200 °C(Solv: ethanol (64-17-5)) |
| Boiling point | 92-93 °C12 mm Hg(lit.) |
| Density | 1.021 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.536(lit.) |
| Flash point | 213 °F |
| Storage conditions | under inert gas (nitrogen or Argon) at 2–8 °C |
| Physical state | Liquid |
| pKa (acidity coefficient) | pK1: 4.24(+2)pK2: 9.78(+1) (25°C,μ=0.05) |
| Specific gravity | 1.021 |
| Color | Clear colorless to yellow |
| Solubility | Soluble in water (partly), and most common polar solvent. Insoluble in non-polar solvents, and oils. |
| Sensitivity | Air Sensitive |
| BRN | 111208 |
| InChI | 1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2 |
| InChIKey | XPQIPUZPSLAZDV-UHFFFAOYSA-N |
| SMILES | NCCc1ccccn1 |
| CAS DataBase Reference | 2706-56-1(CAS DataBase Reference) |
| FDA UNII | ATW1AH7OJ5 |
| NIST Chemistry Reference | 2-Pyridineethanamine(2706-56-1) |
| EPA Substance Registry System | 2-Pyridineethanamine (2706-56-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Target organs | Respiratory system |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard symbols | Xi |
| Risk statements (R) | 36/37/38-34 |
| Safety statements (S) | 26-36-45-36/37/39 |
| UN transport number | 2735 |
| Water hazard class (WGK) | 3 |
| F | 10-34 |
| TSCA inventory status | TSCA listed |
| Hazard class | 8Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Packing group | III |
| Customs code | 29333990 |
| Storage class | 10 - Combustible liquids |
Safety & Regulations
| GHS classification | DangerH314 (14.9%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H315 (85.1%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (85.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (85.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 47 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Skin Corr. 1B (14.9%)Skin Irrit. 2 (85.1%)Eye Irrit. 2 (85.1%)STOT SE 3 (85.1%) |
| F | 10-34 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Water hazard class (WGK) | 3 |
| TSCA inventory status | TSCA listed |
| UN transport number | 2735 |
| Customs code | 29333990 |
| Risk statements (R) | 36/37/38-34 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | Xi |
| Safety statements (S) | 26-36-45-36/37/39 |
| Hazard class | 8Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Storage class | 10 - Combustible liquids |
| Packing group | III |
| Target organs | Respiratory system |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Applications & Uses
Uses
2-(2-Aminoethyl)pyridine is used as active pharmaceutical ingredients.