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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168445Generated: October 23, 2026

Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → 2-{3-[2-(3-Methoxyphenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic Acid

https://huagongshe.com/en/reaction/1168445

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 21980299—
Reactant4-Iodomethyl-2-(3-methoxyphenyl)-5-methyloxazoleHCID 21980316—
Product2-{3-[2-(3-Methoxyphenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic AcidHCID 22493655—

Reaction Steps

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(3-methoxyphenyl)4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 53 of molecular weight 465.55 (C27H31NO6), MS(ESI): 466.37 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06624185B2
Source datasetuspto-grants-2003_09
ORD IDord-128d014cc06b4c33a829d744e7f7f0c7
Source noteuspto-grants-2003_09