HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxy-N-methylbenzylamine → 5-((3,5-dichloropyridin-4-yl)thio)-N-(3-methoxybenzyl)-N-methyl-4-nitrothiophene-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxy-N-methylbenzylamine | HCID 5152225 | — |
| Reactant | 5-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid | HCID 60207317 | — |
| Product | 5-((3,5-dichloropyridin-4-yl)thio)-N-(3-methoxybenzyl)-N-methyl-4-nitrothiophene-2-carboxamide | HCID 46932707 | — |
Reaction Steps
Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (35 mg, 0.1 mmol) and 1-(3-methoxyphenyl)-N-methyl-methanamine (18.0 mg, 0.12 mmol). The title compound was obtained as a solid (18.5 mg, 38% yield). MS m/z: 484.01, 486.01 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680139B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-b8f352ac19194c9abe5e0baf18162e66 |
| Source note | uspto-grants-2014_03 |