HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropaneacetic acid → N-(Cyclopropylacetyl)-L-alanine Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropaneacetic acid | HCID 138440 | — |
| Reactant | Alanine methyl ester hydrochloride | HCID 2733257 | — |
| Product | N-(Cyclopropylacetyl)-L-alanine Methyl Ester | HCID 53934383 | — |
Reaction Steps
Following General Procedure A above using cyclopropylacetic acid (Aldrich) and L-alanine methyl ester hydrochloride (Sigma), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.15 in 25% ethyl acetate/hexanes) and purification was by flash column chromatography using 25% ethyl acetate/hexanes as the eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07390801B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-0f0e1de8b7ee492c95e8d53e5344dce5 |
| Source note | uspto-grants-2008_06 |