HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-chloro-1-methyl-1H-indole-3-carbaldehyde → 5-chloro-1-methyl-3-(methylaminomethyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-chloro-1-methyl-1H-indole-3-carbaldehyde | HCID 16723796 | — |
| Reactant | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| Product | 5-chloro-1-methyl-3-(methylaminomethyl)-1H-indole | HCID 22139017 | 93% |
Reaction Steps
According to the procedure of Preparation 13 (c), except substituting 5-chloro-1-methyl-1H-indole-3-carboxaldehyde for the, 3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (2.1 g, 93%) was obtained as an amber oil: MS (ES) m/e 209.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879872B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-e9af886dc3084fdd815b2ac20e4246be |
| Source note | uspto-grants-2011_02 |