HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → 1-(3,4-Dimethylphenyl)-3-methyl-3-pyrazolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | 1-(3,4-Dimethylphenyl)hydrazine hydrochloride | HCID 173740 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 1-(3,4-Dimethylphenyl)-3-methyl-3-pyrazolin-5-one | HCID 11735829 | — |
Reaction Steps
A solution of 3,4-dimethylphenylhydrazine hydrochloride (17.7 g; 0.1 mol.), ethyl acetoacetate (13.0 g; 0.1 mol.) and sodium acetate (8.2 g; 0.1 mol.) in glacial acetic acid; (250 mL) was stirred and heated under reflux for 24 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160870B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-23628097b02d4c7785b65863c79b4bb1 |
| Source note | uspto-grants-2007_01 |