Isopropylamine → N-isopropylindoline-5-carboxamide

HRID 1468004

Reaction equation

[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([C:10]([OH:12])=O)=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[CH3:13][CH:14]([NH2:16])[CH3:15]>>[CH:14]([NH:16][C:10]([C:6]1[CH:5]=[C:4]2[C:9](=[CH:8][CH:7]=1)[NH:1][CH2:2][CH2:3]2)=[O:12])([CH3:15])[CH3:13]

Participants

Reactant 2

HCID 6363Isopropylamine

HCID 8899763Indoline-5-Carboxylic Acid

Product 1

HCID 28286779N-isopropylindoline-5-carboxamide

Procedure

The title compound was prepared by following the similar procedure as described in Intermediate-10 using indoline-5-carboxylic acid and propan-2-amine (0.315 g, 31%); MS: 205 (M+1).

Sources & evidence

ORD record: ord-9080fa30eadf48d9b743e8b13d299b40
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000175B2

Linked notes

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