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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468021Generated: October 23, 2026

5-(Methylsulfonyl)-1H-indole → tert-Butyl-3-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl)oxy)-azetidine-1-carboxylate

https://huagongshe.com/en/reaction/1468021

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Methylsulfonyl)-1H-indoleHCID 14973230—
ReactantTert-butyl-3-((6-chloropyridin-3-yl)oxy)azetidine-1-carboxylateHCID 86696196—
Producttert-Butyl-3-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl)oxy)-azetidine-1-carboxylateHCID 67807054—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Example-1 by using tert-butyl 3-((6-chloropyridin-3-yl)oxy)azetidine-1-carboxylate (intermediate-9) and 5-(methylsulfonyl)-1H-indole (intermediate-21).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-256eb04dc97d4e1fab68fb17b38855dd
Source noteuspto-grants-2015_04