HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490913Generated: October 24, 2026
2-Methyl-7-(trifluoromethyl)quinoline → HCID 178422399, compound
https://huagongshe.com/en/reaction/1490913
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-7-(trifluoromethyl)quinoline | HCID 22416904 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 4,4'-Di-tert-butyl-2,2'-bipyridyl | HCID 4249187 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | tert-Butyl methyl ether | HCID 15413 | — |
| Product | HCID 178422399 | HCID 178422399 | 57% |
| Product | HCID 178422497 | HCID 178422497 | 38% |
Reaction Steps
Application of general procedure A to 2-methyl-7-(trifluoromethyl)quinoline (211 mg, 1.00mmol) afforded 2 monoborylated products as a 60:40 ratio.
Provenance & Evidence
| DOI | 10.1039/c2sc20776a |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-297c3aeb46f14a219f8a39f08fe03a57 |
|---|
| Source note | Borylation dataset from Roche |
|---|
