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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 151117Generated: October 23, 2026

1,2-Dichloroethane → {4-[2-(3,4,5-Trimethoxy-phenyl)-acetyl]-piperazin-1-yl}-acetic acid ethyl ester

https://huagongshe.com/en/reaction/151117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantNitrogenHCID 947—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant3,4,5-Trimethoxyphenylacetic acidHCID 70372—
ReactantEthyl piperazine-1-acetateHCID 207112—
Product{4-[2-(3,4,5-Trimethoxy-phenyl)-acetyl]-piperazin-1-yl}-acetic acid ethyl esterHCID 59785709—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-2aaf845882a44456bed0a838b12ac658
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)