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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1591633Generated: October 23, 2026

1H-Indazol-5-amine → [4-Chloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazin-2-YL]-(1H-indazol-5-YL)-amine

https://huagongshe.com/en/reaction/1591633

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indazol-5-amineHCID 88012—
Reactant2,4-Dichloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazineHCID 85827032—
Product[4-Chloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazin-2-YL]-(1H-indazol-5-YL)-amineHCID 865889727%

Reaction Steps

The reaction of 2,4-dichloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazine and 5-aminoindazole using the method described in Example 37 provided the title compound (7% yield). 1H NMR (DMSO-d6) 12.95 (s, 1H), 9.52 (br s, 1H), 8.25 (s, 1H), 7.94 (s, 1H), 7.75 (m, 1H), 7.52 (m, 2H), 7.35-7.45 (m, 3H), 7.30 (m, 1H), 7.12)br s, 2H), 2.50 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07291616B2
Source datasetuspto-grants-2007_11
ORD IDord-f3fb07390ba94096a8b50237b2e1f48b
Source noteuspto-grants-2007_11