HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazol-5-amine → [4-Chloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazin-2-YL]-(1H-indazol-5-YL)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazol-5-amine | HCID 88012 | — |
| Reactant | 2,4-Dichloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazine | HCID 85827032 | — |
| Product | [4-Chloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazin-2-YL]-(1H-indazol-5-YL)-amine | HCID 86588972 | 7% |
Reaction Steps
The reaction of 2,4-dichloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazine and 5-aminoindazole using the method described in Example 37 provided the title compound (7% yield). 1H NMR (DMSO-d6) 12.95 (s, 1H), 9.52 (br s, 1H), 8.25 (s, 1H), 7.94 (s, 1H), 7.75 (m, 1H), 7.52 (m, 2H), 7.35-7.45 (m, 3H), 7.30 (m, 1H), 7.12)br s, 2H), 2.50 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07291616B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-f3fb07390ba94096a8b50237b2e1f48b |
| Source note | uspto-grants-2007_11 |