3-nitro-N-(2,1,3-benzothiadiazol-5-yl)-1-benzenesulfonamide → 3-amino-N-(2,1,3-benzothiadiazol-5-yl)-1-benzenesulfonamide

HRID 1620

Reaction equation

HRID 1620 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([S:10]([NH:13][C:14]2[CH:22]=[CH:21][C:17]3=[N:18][S:19][N:20]=[C:16]3[CH:15]=2)(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)([O-])=O>CO.[Ni]>[NH2:1][C:4]1[CH:5]=[C:6]([S:10]([NH:13][C:14]2[CH:22]=[CH:21][C:17]3=[N:18][S:19][N:20]=[C:16]3[CH:15]=2)(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 1

HCID 196919033-nitro-N-(2,1,3-benzothiadiazol-5-yl)-1-benzenesulfonamide

Product 1

HCID 196919403-amino-N-(2,1,3-benzothiadiazol-5-yl)-1-benzenesulfonamide

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 887MethanolSolvent

Procedure

A solution of 1 g of 3-nitro-N-(2,1,3-benzothiadiazol-5-yl)-1-benzenesulfonamide in 25 ml of methanol is hydrogenated to completion on 1 g of Raney Nickel at normal pressure and 20°. The solution is filtered, evaporated and 3-amino-N-(2,1,3-benzothiadiazol-5-yl)-1-benzenesulfonamide is obtained.

Workup

  1. filtrationThe solution is filtered
  2. customevaporated

Sources & evidence

ORD record
ord-6320ae92480446599727eaa48b88a8bc
Source dataset
uspto-grants-1998_03
Patent number
US05726194

Linked notes

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