3,5-Heptanedione → 2-[3-(4-Chlorophenoxy)propyl]-5,7-diethyl-[1,2,4]triazolo[1,5-a]pyrimidine

Participants

Reaction Steps

The title compound was prepared according to the experimentals described for Example 22 above from 3-[3-(4-chlorophenoxy)propyl]-1H-1,2,4-triazol-5-amine and 3,5-heptanedione in 44% yield; 1H NMR (DMSO-d6, 400 MHz) δ ppm: 7.31 (dd, 1H), 7.29 (dd, 1H), 7.11 (s, 1H), 6.96 (dd, 1H), 6.94 (dd, 1H), 4.08 (t, 2H), 3.07 (q, 2H), 2.97 (t, 2H), 2.86 (q, 2H), 2.20 (m, 2H), 1.33 (t, 3H), 1.27 (t, 3H).

Provenance & Evidence