HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glyoxal → Quinoxaline, 6-nitro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glyoxal | HCID 7860 | — |
| Reactant | 4-Nitro-1,2-phenylenediamine | HCID 5111791 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Quinoxaline, 6-nitro- | HCID 96029 | 97.1% |
Reaction Steps
A suspension of 4-nitrobenzene-1,2-diamine (15.3 g, 0.1 mol) and oxalaldehyde (40% in water, 17.4 g, 0.12 mol) in EtOH (150 mL) was stirred at reflux for 16 h. The mixture was then filtered, and the solid was collected to give 6-nitroquinoxaline as a yellow solid (17.0 g, yield 97%). ESI MS: m/z 176.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249162B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-cc9071194f8f47d59f94dee23856f614 |
| Source note | uspto-grants-2016_02 |