2-Aminophenol → HCID 23106862, compound

HRID 1782552

Reaction equation

I[CH:2]([CH2:4][CH2:5][CH2:6][CH3:7])[CH3:3].[NH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[OH:15]>>[CH3:3][CH:2]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[OH:15])[CH2:4][CH2:5][CH2:6][CH3:7]

Participants

Reactant 2

HCID 58012-Aminophenol

HCID 330192-Iodohexane

Product 1

HCID 23106862HCID 23106862, compound

Procedure

The same procedure as in Example 4 was repeated except for using 2-iodohexane in place of 2-iodobutane, to conduct the reaction. As a result, it was confirmed that the rate of conversion of o-aminophenol was 93%, the selectivity to the N-monoalkylated compound was 41% and the oxygen absorption initiation time as an index of determining an oxidation-inhibiting property thereof was 320 min.

Workup

customthe reaction
customthe oxygen absorption initiation time as an index

Sources & evidence

ORD record: ord-a4f48cb693294aaea3c29805e7a8377b
Source dataset: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07498467B2

Linked notes

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