2-Amino-5-fluoropyridine → (5-Fluoro-pyridin-2-yl)-[1,7]naphthyridin-8-yl-amine

HRID 1787589

Reaction equation

HRID 1787589 reaction equation
Cl[C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[CH:9][CH:8]=[CH:7]2.[NH2:12][C:13]1[CH:18]=[CH:17][C:16]([F:19])=[CH:15][N:14]=1>>[F:19][C:16]1[CH:17]=[CH:18][C:13]([NH:12][C:2]2[N:3]=[CH:4][CH:5]=[C:6]3[C:11]=2[N:10]=[CH:9][CH:8]=[CH:7]3)=[N:14][CH:15]=1

Participants

3

Reactant 2

HCID 27377012-Amino-5-fluoropyridineHCID 123427128-Chloro-(1,7)naphthyridine

Product 1

HCID 57600354(5-Fluoro-pyridin-2-yl)-[1,7]naphthyridin-8-yl-amine

Procedure

The title compound, MS: m/e=241.2 (M+H+), was prepared in accordance with the general method of example 1 from 8-chloro-[1,7]naphthyridine and 2-amino-5-fluoropyridine.

Sources & evidence

ORD record
ord-1467d2b8ac21406eb7f657c5285b5d8b
Source dataset
uspto-grants-2009_03
Patent number
US07511055B2

Linked notes

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