HuagongsheHuagongshe Chemistry Print Report · For research reference only
D-Tryptophan benzyl ester → (R)-alpha-[(3-t-Butoxycarbonylamino-3-methyl-1-oxobutyl)amino]-1-H-indole-3-propanoic acid benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | D-Tryptophan benzyl ester | HCID 6995075 | — |
| Reactant | 3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid | HCID 10376046 | — |
| Product | (R)-alpha-[(3-t-Butoxycarbonylamino-3-methyl-1-oxobutyl)amino]-1-H-indole-3-propanoic acid benzyl ester | HCID 86752263 | — |
Reaction Steps
Prepared from D-tryptophan benzyl ester (1 g; 3.40 mmol) and 3-t-butoxycarbonylamino-3-methylbutanoic acid (0.91 g; 4.19 mmol) by the procedure described in Example 6, Step C. The yield was 0.981 g (58%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05726319 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-e392efa1dd0c43839d8e3026d6f4b2ee |
| Source note | uspto-grants-1998_03 |