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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 196439Generated: October 24, 2026

1,1-Dimethylethyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate → Tert-butyl 1-[5-[(3,5-difluorophenyl)carbamoyl]-3-pyridinyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxylate

https://huagongshe.com/en/reaction/196439

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1-Dimethylethyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylateHCID 22562205—
Reactant5-bromo-N-(3,5-difluorophenyl)nicotinamideHCID 41601149—
ProductTert-butyl 1-[5-[(3,5-difluorophenyl)carbamoyl]-3-pyridinyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxylateHCID 67265700—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-f98077fe217647229aff89db12db3f38
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)