HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Propylboronic acid → N-(4-tert-butyl-benzyl)-3-chloro-N-[2-(3-fluoro-5-trifluoromethyl-phenyl)-ethyl]-5-propyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Propylboronic acid | HCID 351065 | — |
| Reactant | 3-bromo-N-(4-tert-butyl-benzyl)-5-chloro-N-[2-(3-fluoro-5-trifluoromethyl-phenyl)-ethyl]-benzamide | HCID 86613994 | — |
| Product | N-(4-tert-butyl-benzyl)-3-chloro-N-[2-(3-fluoro-5-trifluoromethyl-phenyl)-ethyl]-5-propyl-benzamide | HCID 68561213 | — |
Reaction Steps
The title compound was prepared in analogy to example 3, using 3-bromo-N-(4-tert-butyl-benzyl)-5-chloro-N-[2-(3-fluoro-5-trifluoromethyl-phenyl)-ethyl]-benzamide (Example B177) and n-propylboronic acid. 534.3 [ISP (M+H)+]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745477B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-e4164ec0b4f04dbcb326a5f2cfbbf628 |
| Source note | uspto-grants-2010_06 |