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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105859Generated: October 23, 2026

Chloroacetyl chloride → N-methoxy-N-methyl-2-piperazin-1-yl-acetamide

https://huagongshe.com/en/reaction/2105859

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetyl chlorideHCID 6577—
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
ProductN-methoxy-N-methyl-2-piperazin-1-yl-acetamideHCID 57809253—

Reaction Steps

The title compound was prepared from 1-tert-butyloxycarbonyl-piperazine, chloroacetylchloride and N-methoxy-N-methylamine in an analogous manner as described in example 21.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579368B2
Source datasetuspto-grants-2009_08
ORD IDord-454bc75ae56a44cb9aa871131ba39e28
Source noteuspto-grants-2009_08