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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2119617Generated: October 23, 2026

4-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid → 5-FLUORO-1-METHYL-1,4-DIHYDRO-9H-PYRAZOLO[4,3-b]QUINOLIN-9-ONE

https://huagongshe.com/en/reaction/2119617

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acidHCID 12985693—
Reactant4-[(2-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acidHCID 12985695—
Product5-FLUORO-1-METHYL-1,4-DIHYDRO-9H-PYRAZOLO[4,3-b]QUINOLIN-9-ONEHCID 12985696—

Reaction Steps

The title compound was prepared according to the procedure of step 2 in EXAMPLE 1 (CJ-022998) using 4-[(2-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid (EXAMPLE 2, step 1), instead of 4-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06686373B2
Source datasetuspto-grants-2004_02
ORD IDord-11a8c2c1b7f743138466d08d7696c4ea
Source noteuspto-grants-2004_02