HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromohexadecane → 4-amino-1-[[(5S)-2-hexadecoxy-2-oxo-1,4,2$l^{5}-dioxaphosphinan-5-yl]methyl]pyrimidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromohexadecane | HCID 8213 | — |
| Reactant | Cyclic HPMPC | HCID 122873 | — |
| Product | 4-amino-1-[[(5S)-2-hexadecoxy-2-oxo-1,4,2$l^{5}-dioxaphosphinan-5-yl]methyl]pyrimidin-2-one | HCID 483472 | 55% |
Reaction Steps
The title compound was prepared using the same procedure as described for Example 1 using 1-bromohexadecane and cyclic cidofovir.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193167B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-6abf863f88864c4eae7650480f24dadc |
| Source note | uspto-grants-2012_06 |