HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → N'-t-butyl-N-(2-hydroxymethylbenzoyl)hydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phthalide | HCID 6885 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | tert-Butylhydrazine | HCID 81890 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N'-t-butyl-N-(2-hydroxymethylbenzoyl)hydrazine | HCID 19368051 | 13.5% |
Reaction Steps
t-Butylhydrazine (0.1 mol) in 75 ml ethanol was treated with 50% aqueous sodium hydroxide (0.11 mol). Phthalide (0.1 mol) was added and the mixture was refluxed for 5 days. After cooling, water was added and the crude product was isolated by filtration. Filtration through silica gel afforded N'-t-butyl-N-(2-hydroxymethylbenzoyl)hydrazine (3.0 g): m.p. 116°-118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05424333 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-70f1a15021854145b1b9c22f57f6e88f |
| Source note | uspto-grants-1995_06 |