HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220607Generated: October 24, 2026
O-Phenylenediamine → Benzo[b][1,4]benzodiazepin-6-one
https://huagongshe.com/en/reaction/220607
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | O-Phenylenediamine | HCID 7243 | — |
| Reactant | Isatoic Anhydride | HCID 8359 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | Benzo[b][1,4]benzodiazepin-6-one | HCID 19781529 | 96% |
Reaction Steps
A mixture of isatoic anhydride (1 mol) and 1,2 phenylenediamine (1.1 mol) in aglacial acetic acid (60%) was heated at 75° C. for 3 hrs. The resulting mixture was diluted with water and solid filtered to obtained dibenzo[b,e][1,4]-diazepine-11-one in 96% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08202989B2 |
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| Source dataset | uspto-grants-2012_06 |
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| ORD ID | ord-2936c68d6a464830925ee60bd4de99dd |
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| Source note | uspto-grants-2012_06 |
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