Triethyloxonium tetrafluoroborate → Ethyl 4-chloro-2-fluorobenzimidate

HRID 2232456

Reaction equation

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[C:4]([F:11])[CH:3]=1.F[B-](F)(F)F.[CH2:17]([O+](CC)CC)[CH3:18]>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](=[NH:8])[O:7][CH2:17][CH3:18])=[C:4]([F:11])[CH:3]=1

Participants

Reactant 2

HCID 2723982Triethyloxonium tetrafluoroborate

HCID 37218494-Chloro-2-fluorobenzamide

Product 1

HCID 19373098Ethyl 4-chloro-2-fluorobenzimidate

Procedure

starting from 4-chloro-2-fluorobenzamide and triethyloxonium tetrafluoroborate there is obtained ethyl 4-chloro-2-fluorobenzimidate as an oil; mass spectrum: 202 (3.5), 201 (1), 200 (10), 182 (2), 173 (27), 157 (100), 156 (75);

Sources & evidence

ORD record: ord-9015969e3d704a7ca5621d033eedd6d4
Source dataset: uspto-grants-1988_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04788210

Linked notes

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