Ethylene Glycol → 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol

Participants

Reaction Steps

A solution of 1,8-dichloro-3,6-dioxaoctane (40 g) and potassium hydroxide (11.8 g) in ethylene glycol (100 ml) was stirred at 100° C. for 18 h. The mixture was then cooled, filtered and the residue washed with acetone (2×35 ml). The combined filtrate was then distilled to yield the product as a clear oil (13.5 g, 30%), b.p. 120°-122° C./0.2 mm Hg; I.r. (liquid film) 3430 cm-1.

Provenance & Evidence