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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2257186Generated: October 23, 2026

Dimethylamine → 5-Nitro-6-dimethylaminoquinoline

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Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant6-Chloro-5-nitroquinolineHCID 4070800—
Product5-Nitro-6-dimethylaminoquinolineHCID 19027869—

Reaction Steps

5-Nitro-6-chloroquinoline, prepared as described by Manske & Kulka, Organic Reactions, Vol. VII, 59 (1953) and Campbell et al., J. Am. Chem. Soc., 68, 1559 (1946), was allowed to react with dimethylamine to yield 5-nitro-6-dimethylaminoquinoline. This material was converted to the title compound by the procedure described in Example 33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05656634
Source datasetuspto-grants-1997_08
ORD IDord-aaeee53c8bd74854b4c49490fa0f8acd
Source noteuspto-grants-1997_08