HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4,6-dimethylpyrimidine → 1-[(4,6-Dimethyl-2-pyrimidinyl)]-4-[[4-[[7-chloro-4-quinolinyl]amino]phenyl]sulfonyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4,6-dimethylpyrimidine | HCID 20550 | — |
| Reactant | [[4-[(7-Chloro-4-quinolinyl)amino]phenyl]sulfonyl]piperazine | HCID 54297387 | — |
| Product | 1-[(4,6-Dimethyl-2-pyrimidinyl)]-4-[[4-[[7-chloro-4-quinolinyl]amino]phenyl]sulfonyl]piperazine | HCID 21314934 | — |
Reaction Steps
In the manner given in Example 9, part E, 2-chloro-4,6-dimethylpyrimidine is heated with [[4-[(7-chloro-4-quinolinyl)amino]phenyl]sulfonyl]piperazine to give 1-[(4,6-dimethyl-2-pyrimidinyl)]-4-[[4-[[7-chloro-4-quinolinyl]amino]phenyl]sulfonyl]piperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04159331 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-a4e7b78715994fb29acec40919aa7af3 |
| Source note | uspto-grants-1979_06 |