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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391813Generated: October 24, 2026

4-(4-Ethylpiperazin-1-yl)aniline → 8-(2,6-Dimethyl-phenyl)-quinoxaline-5-carboxylic acid [4-(4-ethyl-piperazin-1-yl)phenyl]-amide

https://huagongshe.com/en/reaction/2391813

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Ethylpiperazin-1-yl)anilineHCID 936738—
Reactant8-(2,6-Dimethyl-phenyl)quinoxaline-5-carboxylic acidHCID 66914574—
Product8-(2,6-Dimethyl-phenyl)-quinoxaline-5-carboxylic acid [4-(4-ethyl-piperazin-1-yl)phenyl]-amideHCID 44516605—

Reaction Steps

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 4-(4-ethylpiperazin-1-yl)aniline (Step 1.9) and 8-(2,6-dimethyl-phenyl)-quinoxaline-5-carboxylic acid (Example 71). Title compound: ESI-MS: 466.2 [M+H]+; tR=3.67 min (System 3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273882B2
Source datasetuspto-grants-2012_09
ORD IDord-08222685d94f43aa9db2f607c73e6721
Source noteuspto-grants-2012_09