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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240607Generated: October 23, 2026

2-Fluoro-3-nitropyridine → 3-Nitro-2-[(R)-(tetrahydro-pyran-3-yl)oxy]-pyridine

https://huagongshe.com/en/reaction/240607

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-3-nitropyridineHCID 2762817—
Reactant(R)-Tetrahydro-2H-pyran-3-OLHCID 12256034—
Product3-Nitro-2-[(R)-(tetrahydro-pyran-3-yl)oxy]-pyridineHCID 58413156—

Reaction Steps

Prepared analogously to I.1 from 2-fluor-3-nitropyridine and (R)-tetrahydro-pyran-3-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648068B2
Source datasetuspto-grants-2014_02
ORD IDord-c8dca916f087456e85d80ce6911ccd18
Source noteuspto-grants-2014_02