5-Chlorooxindole → 5-Chloro-3-(2,3-dihydro-benzofuran-5-ylmethylene)-1,3-dihydroindol-2-one

HRID 24359

Reaction equation

HRID 24359 reaction equation
[CH:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:10][CH2:9][CH2:8][C:7]=2[CH:11]=1)=O.[Cl:12][C:13]1[CH:14]=[C:15]2[C:19](=[CH:20][CH:21]=1)[NH:18][C:17](=[O:22])[CH2:16]2>>[Cl:12][C:13]1[CH:14]=[C:15]2[C:19](=[CH:20][CH:21]=1)[NH:18][C:17](=[O:22])[C:16]2=[CH:1][C:3]1[CH:4]=[CH:5][C:6]2[O:10][CH2:9][CH2:8][C:7]=2[CH:11]=1

Participants

3

Reactant 2

HCID 1528015-ChlorooxindoleHCID 7359012,3-Dihydrobenzofuran-5-carboxaldehyde

Product 1

HCID 541779635-Chloro-3-(2,3-dihydro-benzofuran-5-ylmethylene)-1,3-dihydroindol-2-one

Procedure

2,3-Dihydro-5-formylbenzofuran was condensed with 5-chloro-2-oxindole to give 0.25 g of 5-Chloro-3-(2,3-dihydro-benzofuran-5-ylmethylene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-519f9e4e53ff4fd4825af43ea0ea85c6
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Linked notes

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