HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diketene → Acetoacetic acid N-[4-(6-oxo-1,4,5,6-tetrahydropyridazin-3yl)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diketene | HCID 12661 | — |
| Reactant | 6-(4-Aminophenyl)-4,5-dihydropyridazin-3(2H)-one | HCID 676750 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Acetoacetic acid N-[4-(6-oxo-1,4,5,6-tetrahydropyridazin-3yl)-phenyl]-amide | HCID 13646979 | — |
Reaction Steps
20 g (0.106 mole) of 3-(4-aminophenyl)-6-oxo-1,4,5,6-tetrahydropyridazine in 250 ml of dimethylformamide are stirred with 9.47 g (0.113 moles) of diketene for 12 hours at room temperature. After the mixture has been concentrated, the residue is boiled up with 100 ml of ethanol, and the product is filtered off after cooling.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04707479 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-06341a1303b7490f95e684614b1007ea |
| Source note | uspto-grants-1987_11 |