HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-methoxyphenyl)-N-methylmethanamine → 4-(N-(4-methoxybenzyl)-N-methylamino)-1-(4-nitrophenyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-methoxyphenyl)-N-methylmethanamine | HCID 485407 | — |
| Reactant | 1-(4-Nitrophenyl)piperidin-4-one | HCID 3842562 | — |
| Product | 4-(N-(4-methoxybenzyl)-N-methylamino)-1-(4-nitrophenyl)piperidine | HCID 19784354 | 72.4% |
Reaction Steps
3.0 g (13.6 mmol) of 1-(4-nitrophenyl)-4-piperidone and 2.0 g (13.6 mmol) of N-(4-methoxybenzyl)-N-methylamine were reacted in a similar manner to Example 1. 3.5 g of 4-(N-(4-methoxybenzyl)-N-methylamino)-1-(4-nitrophenyl)piperidine were obtained. Melting point 144°-145° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05260318 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-7f9b91675af14320a1c9c71b9336bdf2 |
| Source note | uspto-grants-1993_11 |