HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → 3-(4-Chloro-3-sulfamoylbenzoyl)-1,2-dimethylindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | 1,2-Dimethylindole | HCID 13408 | — |
| Reactant | 3-(Aminosulfonyl)-4-chlorobenzoyl chloride | HCID 3017979 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | 3-(4-Chloro-3-sulfamoylbenzoyl)-1,2-dimethylindole | HCID 21316638 | — |
Reaction Steps
is obtained as described in Example 10 (a) from 10 g 4-chloro-3-sulfamoylbenzoyl chloride and 6.53 g 1,2-dimethylindole in dichloro-ethane in the presence of 12 g aluminum chloride. After treatment with isopropanol, crystals having a melting point of 247°-249° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04156732 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-a3b045773a7b453484155875cccb118d |
| Source note | uspto-grants-1979_05 |