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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 264352Generated: October 24, 2026

1-Bromohexane → Methyl 5-n-hexyloxy-2-hydroxybenzoate

https://huagongshe.com/en/reaction/264352

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-BromohexaneHCID 8101—
ReactantMethyl GentisateHCID 75077—
ProductMethyl 5-n-hexyloxy-2-hydroxybenzoateHCID 1903668658%

Reaction Steps

Synthesis was carried out in the same manner as in Example 1, except for replacing methyl 2,4-dihydroxybenzoate with methyl 2,5-dihydroxybenzoate and replacing 2-ethylhexyl bromide with n-hexyl bromide, to obtain methyl 5-n-hexyloxy-2-hydroxybenzoate represented by the following chemical formula (hereinafter referred to as compound 12) as a colorless, clear and oily substance in a yield of 58%. The analytical results are shown below. ##STR33##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05646184
Source datasetuspto-grants-1997_07
ORD IDord-067a1c54dc8644329a2034184a965103
Source noteuspto-grants-1997_07