HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamidine acetate → 6,7,8,9-Tetrahydro-5H-5,9-methanopyrimido[4,5-d]azepin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamidine acetate | HCID 160693 | — |
| Reactant | 10-Benzyl-4-methyl-3,5,10-triaza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-triene | HCID 59837825 | — |
| Product | 6,7,8,9-Tetrahydro-5H-5,9-methanopyrimido[4,5-d]azepin-2-amine | HCID 68805564 | — |
Reaction Steps
Following the method described in Example 13, 10-benzyl-4-methyl-3,5,10-triaza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-triene and formamidine acetate were converted to the title compound in 18% overall yield. APCl MS m/z 177.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456177B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-c1d4b54bac994441950d571e40c8920c |
| Source note | uspto-grants-2008_11 |