HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethyl-4-cyanophenyl isothiocyanate → 2-(4-Cyano-2-ethylphenylimino)-3-(4-chlorobenzyl)-1,3-thiazolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethyl-4-cyanophenyl isothiocyanate | HCID 18316102 | — |
| Reactant | N-(4-chlorobenzyl)-N-(2-chloroethyl)ammonium chloride | HCID 18316438 | — |
| Product | 2-(4-Cyano-2-ethylphenylimino)-3-(4-chlorobenzyl)-1,3-thiazolidine | HCID 18316094 | — |
Reaction Steps
2-Hydroxyethylamine was reacted with 4-chlorobenzyl bromide according to Method B2a to give N-(4-chlorobenzyl)-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-(4-chlorobenzyl)-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 4-cyano-2-ethylphenyl isothiocyanate to give 2-(4-cyano-2-ethylphenylimino)-3-(4-chlorobenzyl)-1,3-thiazolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06353006B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-3458ebfbe13b4a778daf071b0cae48e9 |
| Source note | uspto-grants-2002_03 |