HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)phenylglyoxal → N-(3-(4-Methylphenyl)propyl)-2-hydroxy-2-(3-trifluoromethylphenyl)ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)phenylglyoxal | HCID 2783284 | — |
| Reactant | 3-(4-Methylphenyl)propan-1-amine | HCID 12564270 | — |
| Product | N-(3-(4-Methylphenyl)propyl)-2-hydroxy-2-(3-trifluoromethylphenyl)ethanamine | HCID 23322159 | — |
Reaction Steps
The title compound was prepared in the manner described in Example 9 using 3-trifluoromethylphenylglyoxal and 3-(4-methylphenyl)propanamine. Recrystallization of the chromatographed material from hexane gave the title compound m.p. 96-98. τ(CDCl3) 8.0-8.5 (2H, m), 7.7 (3H, s), 7.0-7.5 (6H, m+2H, disappears with D2O), 5.3 (1H, dd), 2.9 (4H, s), 2.3-2.7 (4H, m).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588749 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-a43d5886af2b4183ae5193bb0f0e2f07 |
| Source note | uspto-grants-1986_05 |