2-Amino-4-(4-chlorophenyl)thiazole → 3-Pyridinecarboxamide, N-(4-(4-chlorophenyl)-2-thiazolyl)-

HRID 28117

Reaction equation

HRID 28117 reaction equation
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]2[N:18]=[C:19]([NH2:22])[S:20][CH:21]=2)=[CH:13][CH:12]=1>>[Cl:10][C:11]1[CH:12]=[CH:13][C:14]([C:17]2[N:18]=[C:19]([NH:22][C:1](=[O:8])[C:2]3[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=3)[S:20][CH:21]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 732412-Amino-4-(4-chlorophenyl)thiazoleHCID 82604Nicotinoyl chloride

Product 1

HCID 6847163-Pyridinecarboxamide, N-(4-(4-chlorophenyl)-2-thiazolyl)-

Procedure

In a manner similar to that described in Example 5 but using nicotinoyl chloride and 4-parachlorophenyl 2-amino thiazole, there is obtained a product of the formula: ##STR11##

Workup

  1. customthere is obtained a product of the formula

Sources & evidence

ORD record
ord-24b3619abbe349148e0d084bd5fe1995
Source dataset
uspto-grants-1980_09
Patent number
US04225610

Linked notes

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